Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953417 | 0.85 | TSHR (0.44) | TDP1TSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL16960018 | 0.83 | KDM4E (0.39) | KDM4ETDP1TSHRGLASMN1; SMN2 | |
| SCHEMBL16950830 | 0.81 | HPGD (0.47) | KDM4ETSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL16959823 | 0.81 | KDM4E (0.39) | KDM4ESMN1; SMN2MEN1USP2ALDH1A1 | |
| SCHEMBL16961775 | 0.81 | ADRA1A (0.54) | TSHRLMNAHTTMEN1ALDH1A1 | |
| SCHEMBL16958455 | 0.80 | MEN1 (0.40) | TDP1LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL16956830 | 0.79 | LMNA (0.41) | KDM4ETDP1TSHRGLASMN1; SMN2 | |
| SCHEMBL16956011 | 0.77 | CA1 (0.33) | PYCR1 | |
| SCHEMBL16955715 | 0.77 | HSP90AA1 (0.34) | TDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL16595240 | 0.77 | SMN1; SMN2 (0.42) | KDM4ETDP1TSHRGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |