Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491844 | 0.86 | ERN1 (0.53) | AKR1C3AKR1C2ERN1TDP1HSPB1 | |
| SCHEMBL16961423 | 0.85 | AKR1C3 (0.44) | AKR1C3AKR1C2ERN1TDP1HSPB1 | |
| SCHEMBL11858606 | 0.82 | ERN1 (0.46) | ERN1TDP1HSPB1HTTMEN1 | |
| SCHEMBL9367150 | 0.80 | AKR1C3 (0.50) | AKR1C3AKR1C2TDP1HSPB1HTT | |
| SCHEMBL8045670 | 0.80 | TDP1 (0.58) | ERN1TDP1HTTMEN1MAPT | |
| SCHEMBL16959001 | 0.80 | AKR1C3 (0.44) | AKR1C3AKR1C2TDP1HSPB1HTT | |
| SCHEMBL16953209 | 0.79 | MEN1 (0.54) | ERN1TDP1HSPB1HTTMEN1 | |
| SCHEMBL16952799 | 0.78 | AKR1C3 (0.40) | AKR1C3AKR1C2TDP1HSPB1HTT | |
| SCHEMBL397137 | 0.78 | HSPB1 (0.56) | AKR1C3AKR1C2TDP1HSPB1HTT | |
| SCHEMBL30062398 | 0.78 | HSPB1 (0.56) | AKR1C3AKR1C2TDP1HSPB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |