Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950729 | 0.84 | SMN1; SMN2 (0.43) | AKR1C3AKR1C2TDP1HSPB1LMNA | |
| SCHEMBL16956126 | 0.82 | MEN1 (0.44) | TDP1HSPB1LMNASMN1; SMN2MEN1 | |
| SCHEMBL16962137 | 0.81 | TDP1 (0.54) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16961003 | 0.81 | AKR1C3 (0.41) | AKR1C3AKR1C2TDP1HSPB1LMNA | |
| SCHEMBL13332291 | 0.79 | TDP1 (0.44) | AKR1C3AKR1C2TDP1HSPB1LMNA | |
| SCHEMBL16950758 | 0.79 | CYP19A1 (0.48) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16956438 | 0.79 | MAPT (0.49) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16951185 | 0.78 | AKR1C3 (0.42) | AKR1C3AKR1C2TDP1HSPB1LMNA | |
| SCHEMBL9367150 | 0.77 | AKR1C3 (0.50) | AKR1C3AKR1C2TDP1HSPB1LMNA | |
| SCHEMBL16955166 | 0.76 | GPR3 (0.39) | LMNASMN1; SMN2MAPTTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |