Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955861 | 0.86 | GABRB3 (0.35) | IDO1GABRB3GABRA2GABRB2 | |
| SCHEMBL16955433 | 0.83 | HMGCR (0.38) | GABRB2TRPA1 | |
| SCHEMBL16951250 | 0.83 | NPC1 (0.40) | GABRA2GABRB2 | |
| SCHEMBL16957818 | 0.81 | IDO1 (0.36) | IDO1PTGS1NOTUMSIGMAR1HTR2A | |
| SCHEMBL16955179 | 0.81 | HTR2A (0.39) | IDO1MTORSIGMAR1GABRB2HTR2A | |
| SCHEMBL148275 | 0.80 | IDO1 (0.52) | IDO1MTORNOTUMSIGMAR1HTR2A | |
| SCHEMBL16955867 | 0.80 | RXRA (0.36) | PTGS1TRPA1 | |
| SCHEMBL26074528 | 0.80 | IDO1 (0.46) | IDO1NOTUMSIGMAR1GABRB3GABRA2 | |
| SCHEMBL5779021 | 0.80 | CES2 (0.46) | IDO1PTGS1RPS6KA3JAK3CES2 | |
| SCHEMBL16959213 | 0.79 | CHRM2 (0.35) | PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |