Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.57 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564073 | 0.83 | PDE10A (0.60) | PDE10ALGALS3PDE4DGPBAR1CYSLTR1 | |
| SCHEMBL1423674 | 0.79 | PDE10A (0.71) | PDE10ALGALS3PDE4DCYSLTR1 | |
| SCHEMBL2566156 | 0.79 | PDE10A (0.57) | PDE10ALGALS3PDE4DCYP1A2 | |
| SCHEMBL1423981 | 0.77 | PDE10A (0.67) | PDE10ALGALS3PDE4DCYSLTR1 | |
| SCHEMBL31255319 | 0.76 | PARP10 (0.60) | — | |
| SCHEMBL3270032 | 0.75 | GPBAR1 (0.78) | PDE10AGPBAR1CYSLTR1 | |
| SCHEMBL3276740 | 0.75 | ALOX5 (0.53) | PDE10AGPBAR1CYSLTR1CYP1A2 | |
| SCHEMBL1423926 | 0.75 | PDE10A (0.64) | PDE10ALGALS3PDE4D | |
| SCHEMBL202997 | 0.75 | CYSLTR1 (0.81) | GPBAR1CYSLTR1 | |
| SCHEMBL3296677 | 0.75 | CYSLTR1 (0.69) | PDE10AGPBAR1CYSLTR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000519-A1 | ARYL- AND HETEROARYLAMID DERIVATIVES AS PDE10A ENZYME INHIBITOR | H. LUNDBECK A/S (DK) | 2012-01-05 | — | — | WO | claimed |
| WO-2012000519-A1 | ARYL- AND HETEROARYLAMID DERIVATIVES AS PDE10A ENZYME INHIBITOR | H. LUNDBECK A/S (DK) | 2012-01-05 | — | — | WO | disclosed |