Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957145 | 0.82 | TSHR (0.35) | ALDH1A1MAPTKDM4EGAANPC1 | |
| SCHEMBL16957472 | 0.82 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL16955646 | 0.82 | MEN1 (0.33) | MEN1KMT2ANPC1THRB | |
| SCHEMBL16953161 | 0.81 | ALDH1A1 (0.39) | IKBKBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16956400 | 0.81 | HPGD (0.31) | — | |
| SCHEMBL16958066 | 0.81 | DYRK1A (0.33) | KDM4E | |
| SCHEMBL16953973 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL16958945 | 0.81 | KDM4E (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL16956019 | 0.79 | GABRA1 (0.38) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL16960830 | 0.78 | NPC1 (0.44) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |