Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952623 | 0.85 | DYRK1A (0.33) | DYRK1A | |
| SCHEMBL16960328 | 0.83 | — | — | |
| SCHEMBL16956936 | 0.82 | DYRK1A (0.37) | DYRK1AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL16951859 | 0.81 | IKBKB (0.35) | KDM4E | |
| SCHEMBL16957472 | 0.81 | CYP1A2 (0.42) | KDM4ELMNACYP1A2POLBCYP2C19 | |
| SCHEMBL16957145 | 0.81 | TSHR (0.35) | KDM4EPOLB | |
| SCHEMBL16958945 | 0.79 | KDM4E (0.40) | DYRK1AKDM4ELMNACYP1A2POLB | |
| SCHEMBL16956400 | 0.79 | HPGD (0.31) | DYRK1ALMNA | |
| SCHEMBL16953973 | 0.79 | ALDH1A1 (0.36) | KDM4EPOLB | |
| SCHEMBL16956019 | 0.78 | GABRA1 (0.38) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |