Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002824 | 0.88 | ALDH1A1 (0.46) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL30861660 | 0.85 | KIF11 (0.63) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL17115582 | 0.85 | KIF11 (0.63) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL16475651 | 0.85 | ALDH1A1 (0.53) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL16976598 | 0.85 | ALDH1A1 (0.53) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL472520 | 0.84 | ALDH1A1 (0.57) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL29417704 | 0.84 | ALDH1A1 (0.57) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL9901133 | 0.83 | IDO1 (0.51) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL11132179 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPFFR1NPFFR2KDRKIF11 | |
| SCHEMBL18420271 | 0.82 | NPFFR1 (0.48) | ALDH1A1NPFFR1NPFFR2KDRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652153-A | Method for synthesizing organic nitrile compound from aldehyde | 国科大杭州高等研究院 | 2024-09-17 | — | — | CN | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2015149131-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2015-10-08 | — | — | WO | claimed |
| US-6331649-B1 | REDUCING AN OXIME BY CATALYTIC HYDROGENTATION IN SOLVENT CONTAINING AN ACID | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-12-18 | — | — | US | claimed |
| EP-0581079-A1 | Particular 1,4-dihydropyridine-3,5-dicarboxylic acid ester, process for its preparation and its pharmaceutical use | BAYER AG (DE) | 1994-02-02 | — | — | EP | claimed |
| US-12286432-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| CN-119490487-A | Polysubstituted tetrahydrocarbazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-02-21 | — | — | CN | disclosed |
| CN-118652153-A | Method for synthesizing organic nitrile compound from aldehyde | 国科大杭州高等研究院 | 2024-09-17 | — | — | CN | disclosed |
| CN-114096551-B | With A2A2-Benzylidene hydrazino adenosines with adenosine receptor agonistic activity | 中国人民解放军军事科学院军事医学研究院 | 2024-08-13 | — | — | CN | disclosed |
| CN-114380817-B | Benzimidazolo 2-amino-1, 3, 4-thiadiazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | disclosed |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-23 | — | — | US | disclosed |
| EP-0010347-A1 | Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4182774-A | Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof | A. H. ROBINS COMPANY, INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |
| US-4126635-A | ANTICHOLESTEROL, BLOOD PLATELET AGGREGATION INHIBITION | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112095-A | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4063022-A | GASTRIC ACID | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12286432-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | ALDH1A1 1949/4885NPFFR1 17/4885NPFFR2 31/4885 |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | DGKZ, DGKA, DGKG | ALDH1A1 3985/4885NPFFR1 4427/4885NPFFR2 4231/4885 |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | ALDH1A1 4861/4885NPFFR1 1989/4885NPFFR2 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.