Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954875 | 0.81 | CYP1A2 (0.39) | OPRL1SMN1; SMN2OPRM1ACHECYP1A2 | |
| SCHEMBL16962184 | 0.79 | MAP3K14 (0.33) | ALDH1A1 | |
| SCHEMBL16957930 | 0.79 | — | — | |
| SCHEMBL16956408 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16960284 | 0.79 | IDO1 (0.31) | — | |
| SCHEMBL16959127 | 0.79 | HTR1A (0.34) | — | |
| SCHEMBL16952531 | 0.79 | ABCB1 (0.41) | OPRL1 | |
| SCHEMBL16954206 | 0.77 | PNMT (0.50) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL16960031 | 0.77 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL16960204 | 0.77 | OPRL1 (0.36) | OPRL1SMN1; SMN2OPRM1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |