Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959915 | 0.84 | TRPV4 (0.47) | ARUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL16961573 | 0.84 | XDH (0.38) | AR | |
| SCHEMBL16955918 | 0.83 | AR (0.46) | ARKDM4EUSP2ALDH1A1KDM1A | |
| SCHEMBL523615 | 0.80 | AR (0.49) | ARIMPDH2IMPDH1KDM4EUSP2 | |
| SCHEMBL16962581 | 0.78 | AR (0.42) | ARKDM4EUSP2ALDH1A1KDM1A | |
| SCHEMBL16959497 | 0.78 | CYP2A6 (0.38) | ARIMPDH2IMPDH1ALDH1A1CYP11B1 | |
| SCHEMBL16955354 | 0.78 | AMY1A (0.38) | KDM4EALDH1A1 | |
| SCHEMBL17731548 | 0.78 | AR (0.47) | ARIMPDH2IMPDH1KDM4EUSP2 | |
| SCHEMBL17731549 | 0.78 | AR (0.47) | ARIMPDH2IMPDH1KDM4EUSP2 | |
| SCHEMBL18145874 | 0.78 | AR (0.40) | ARALDH1A1KDM1ASLC6A4GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |