SCHEMBL16952452

SCHEMBL16952452

[CH2]C(C)c1cc(I)cc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.33
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16953807 0.86 TACR1 (0.40) TACR1IDO1TDO2
SCHEMBL27567126 0.86 TACR1 (0.40) TACR1IDO1TDO2
SCHEMBL21916355 0.84 GABRA1 (0.34) TACR1IDO1TDO2
SCHEMBL16951842 0.80 TACR1 (0.34) TACR1IDO1TDO2
SCHEMBL16954215 0.79 IDO1 (0.30) IDO1TDO2
SCHEMBL16951143 0.79 GABRA1 (0.37)
SCHEMBL16962046 0.78 RAPGEF4 (0.38) TACR1IDO1TDO2
SCHEMBL16958699 0.78 TACR1 (0.33) TACR1IDO1TDO2
SCHEMBL16959193 0.77 RAPGEF4 (0.39) TACR1IDO1TDO2
SCHEMBL16950402 0.77 NOTUM (0.41) TACR1IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed