Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26945940 | 0.86 | GABRA1 (0.33) | GABRA1GABRB1GABRB2 | |
| SCHEMBL437277 | 0.84 | TACR1 (0.42) | TACR1IDO1TDO2PDE2AHTR2A | |
| SCHEMBL10629252 | 0.84 | TACR1 (0.39) | GABRA1GABRB2TACR1IDO1TDO2 | |
| SCHEMBL16952452 | 0.84 | TACR1 (0.33) | TACR1IDO1TDO2 | |
| SCHEMBL26840302 | 0.81 | HMGCR (0.41) | GABRA1GABRB1GABRB2CYP2D6 | |
| SCHEMBL29009961 | 0.78 | AKR1C3 (0.47) | TACR1CYP2D6 | |
| SCHEMBL10199720 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2TACR1IDO1TDO2 | |
| SCHEMBL21508132 | 0.77 | CES2 (0.35) | TACR1IDO1TDO2PDE2AHTR2A | |
| SCHEMBL8127537 | 0.77 | PDE2A (0.35) | TACR1IDO1TDO2PDE2AHTR2A | |
| SCHEMBL21766566 | 0.77 | RXRA (0.40) | TACR1IDO1TDO2S1PR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941912-B1 | PESTICIDALLY ACTIVE AZOLE AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| EP-3867237-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | US | disclosed |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-20210395217-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-23 | — | — | US | disclosed |
| WO-2020208036-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020079198-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395217-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, CYP51A1 | GABRA1 656/4885GABRB1 731/4885GABRB2 784/4885 |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | GABRA1 658/4885GABRB1 721/4885GABRB2 816/4885 |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | GABRA1 931/4885GABRB1 915/4885GABRB2 937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.