Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962628 | 0.87 | CES2 (0.48) | NOTUMCES2PTGS1NR4A1NR4A2 | |
| SCHEMBL16957311 | 0.84 | NOTUM (0.36) | NOTUM | |
| SCHEMBL16957730 | 0.81 | — | — | |
| SCHEMBL16958330 | 0.81 | CES2 (0.38) | NOTUMCES2GPBAR1CTSLCTSB | |
| SCHEMBL16959185 | 0.81 | CES2 (0.38) | NOTUMCES2DDR1GPBAR1PTGS1 | |
| SCHEMBL13278210 | 0.80 | NOTUM (0.57) | NOTUMCES2DDR1GPBAR1ACP1 | |
| SCHEMBL16958887 | 0.80 | NOTUM (0.36) | NOTUMCES2PTGS1 | |
| SCHEMBL15517073 | 0.80 | NOTUM (0.61) | NOTUMCES2DDR1GPBAR1ACP1 | |
| SCHEMBL16954212 | 0.79 | CES2 (0.37) | NOTUMCES2PTGS1NR4A1NR4A2 | |
| SCHEMBL16955890 | 0.79 | CES2 (0.37) | CES2DDR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |