Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958330 | 0.89 | CES2 (0.38) | CES2NOTUMPTGS1 | |
| SCHEMBL16959185 | 0.89 | CES2 (0.38) | CES2NOTUMRXRARXRBRXRG | |
| SCHEMBL16955890 | 0.87 | CES2 (0.37) | CES2 | |
| SCHEMBL16954212 | 0.87 | CES2 (0.37) | CES2NOTUMRXRARXRBRXRG | |
| SCHEMBL16952496 | 0.87 | NOTUM (0.53) | CES2NOTUMPTGS1NR4A1NR4A2 | |
| SCHEMBL16958887 | 0.84 | NOTUM (0.36) | CES2NOTUMRXRARXRBRXRG | |
| SCHEMBL16958267 | 0.83 | RXRA (0.38) | CES2RXRARXRG | |
| SCHEMBL16959148 | 0.82 | THRB (0.37) | CES2NOTUMRXRARXRBRXRG | |
| SCHEMBL16957410 | 0.81 | CES2 (0.55) | CES2GAAP2RX1 | |
| SCHEMBL16961342 | 0.81 | RXRA (0.43) | NOTUMGAAMAPTRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |