Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 11/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962628 | 0.87 | CES2 (0.48) | CES2 | |
| SCHEMBL16962576 | 0.84 | ACLY (0.35) | ACLY | |
| SCHEMBL16958330 | 0.81 | CES2 (0.38) | CES2RAPGEF4GPBAR1 | |
| SCHEMBL16959185 | 0.81 | CES2 (0.38) | CES2DDR1GPBAR1HDAC3HDAC1 | |
| SCHEMBL15515997 | 0.80 | CES2 (0.43) | CES2DDR1RAPGEF4ACLYAHR | |
| SCHEMBL16952496 | 0.79 | NOTUM (0.53) | CES2DDR1GPBAR1 | |
| SCHEMBL16954212 | 0.79 | CES2 (0.37) | CES2 | |
| SCHEMBL16958887 | 0.77 | NOTUM (0.36) | CES2 | |
| SCHEMBL766178 | 0.77 | CES2 (0.50) | CES2DDR1ACLYGPBAR1HDAC3 | |
| SCHEMBL16958267 | 0.76 | RXRA (0.38) | CES2DDR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |