Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950692 | 0.88 | CES2 (0.50) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16958822 | 0.83 | RXRA (0.40) | RXRARXRB | |
| SCHEMBL16950849 | 0.81 | CES2 (0.39) | CES2RXRARXRBRXRGGPBAR1 | |
| SCHEMBL16962044 | 0.80 | CES2 (0.45) | CES2RAPGEF4GRIN2BADCY8ADCY1 | |
| SCHEMBL16956054 | 0.80 | CES2 (0.38) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16960304 | 0.80 | NOTUM (0.54) | CES2RXRARXRBRXRGGPBAR1 | |
| SCHEMBL16955083 | 0.80 | TPMT (0.44) | RXRARXRB | |
| SCHEMBL16959714 | 0.79 | NOTUM (0.38) | CES2RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL13954751 | 0.77 | CES2 (0.42) | CES2RAPGEF4GRIN2BADCY8ADCY1 | |
| SCHEMBL7786247 | 0.77 | CES2 (0.52) | CES2ADCY8ADCY1PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |