Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 2/20 | 0.36 |
| ▸ | RHOA | P61586 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952545 | 0.88 | CES2 (0.39) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16950849 | 0.88 | CES2 (0.39) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16960304 | 0.87 | NOTUM (0.54) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16956054 | 0.87 | CES2 (0.38) | CES2RXRARXRBRXRGTACR1 | |
| SCHEMBL16959714 | 0.85 | NOTUM (0.38) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16950459 | 0.82 | RXRA (0.42) | CES2RXRARXRG | |
| SCHEMBL16955954 | 0.82 | CES2 (0.35) | CES2RXRARXRBRXRGTACR1 | |
| SCHEMBL16955924 | 0.81 | RXRA (0.45) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16951956 | 0.80 | CES2 (0.56) | CES2GAAP2RX1 | |
| SCHEMBL16955754 | 0.80 | GABRA1 (0.46) | RXRARXRBRXRGGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |