Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952073 | 0.83 | MAPT (0.44) | PTGDR2MEN1KMT2AMAPTHTT | |
| SCHEMBL16956291 | 0.82 | TDP1 (0.51) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL16950729 | 0.82 | SMN1; SMN2 (0.43) | AKR1C3AKR1C2MEN1KMT2AMAPT | |
| SCHEMBL16952799 | 0.81 | AKR1C3 (0.40) | AKR1C3AKR1C2MEN1KMT2AMAPT | |
| SCHEMBL16952486 | 0.81 | MAPT (0.48) | PTGDR2MEN1KMT2AMAPTHTT | |
| SCHEMBL16959952 | 0.80 | CYP19A1 (0.46) | PTGDR2MEN1KMT2AMAPTHTT | |
| SCHEMBL16961858 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AMAPTTP53HTT | |
| SCHEMBL16953128 | 0.77 | GPR3 (0.37) | KMT2A | |
| SCHEMBL16951360 | 0.77 | PDE2A (0.35) | — | |
| SCHEMBL16959001 | 0.77 | AKR1C3 (0.44) | AKR1C3AKR1C2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |