Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951178 | 0.83 | KMT2A (0.36) | NPC1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL16961828 | 0.83 | MEN1 (0.35) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16951972 | 0.81 | CXCR5 (0.33) | MEN1NPC1KMT2AHPGDKDM4E | |
| SCHEMBL16952951 | 0.81 | GABRA1 (0.42) | MEN1KMT2AGABRA1GABRB2HPGD | |
| SCHEMBL16962527 | 0.80 | NPC1 (0.39) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16961987 | 0.80 | GAA (0.40) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL16950629 | 0.80 | ALDH1A1 (0.33) | MEN1NPC1KMT2AGABRA1GABRB2 | |
| SCHEMBL16952460 | 0.80 | KIT (0.34) | — | |
| SCHEMBL68691 | 0.79 | GABRA1 (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16957085 | 0.79 | ADRB1 (0.40) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |