Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394897 | 0.85 | ALDH1A1 (0.58) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL16957180 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL16954828 | 0.83 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL16955809 | 0.83 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL394137 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL11654599 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL397097 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL16957014 | 0.77 | ALDH1A1 (0.62) | SMN1; SMN2L3MBTL1HTTKMT2AALDH1A1 | |
| SCHEMBL446475 | 0.77 | TDP1 (0.55) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL10176626 | 0.77 | ALDH1A1 (0.62) | SMN1; SMN2L3MBTL1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |