Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960196 | 0.89 | MEN1 (0.42) | GSK3ASMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL16959860 | 0.86 | NPC1 (0.52) | GSK3ASMN1; SMN2NFE2L2KMT2APOLB | |
| SCHEMBL16956484 | 0.84 | GSK3A (0.40) | GSK3ASMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL6632658 | 0.83 | NFE2L2 (0.61) | NFE2L2LMNAMAPTKDM4EHPGD | |
| SCHEMBL16950721 | 0.83 | PTGES (0.41) | GSK3ASMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL1125257 | 0.83 | SRC (0.58) | GSK3ASMN1; SMN2NFE2L2SRCTLR2 | |
| SCHEMBL16954031 | 0.83 | GSK3A (0.52) | GSK3ASMN1; SMN2NFE2L2SRCPOLB | |
| SCHEMBL16955698 | 0.82 | GSK3A (0.38) | GSK3ASMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL16955265 | 0.82 | GSK3A (0.38) | GSK3AKMT2APOLBLMNAMEN1 | |
| SCHEMBL16953545 | 0.82 | GSK3A (0.38) | GSK3ANFE2L2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |