Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630185 | 1.00 | HDAC9 (0.40) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL1477982 | 0.86 | EDNRB (0.38) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL1668272 | 0.86 | EDNRB (0.38) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL28476843 | 0.83 | KIF11 (0.37) | HDAC9EDNRBEDNRAKIF11 | |
| SCHEMBL28476847 | 0.83 | KIF11 (0.37) | HDAC9EDNRBEDNRAKIF11 | |
| SCHEMBL4879031 | 0.78 | KIF11 (0.39) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL19644421 | 0.74 | MEN1 (0.40) | MEN1NPSR1 | |
| SCHEMBL3732088 | 0.74 | HDAC9 (0.43) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL27956103 | 0.74 | HDAC9 (0.43) | HDAC9EDNRBEDNRAKIF11MEN1 | |
| SCHEMBL1404156 | 0.72 | HDAC9 (0.41) | HDAC9EDNRBEDNRAKIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310387-A2 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA, D.D., Novo Mesto (SI) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010012459-A2 | A PROCESS FOR THE PREPARATION OF SOLIFENACIN SALTS AND THEIR INCLUSION INTO PHARMACEUTICAL DOSAGE FORMS | KRKA, D.D., NOVO MESTO (SI) | 2010-02-04 | — | — | WO | disclosed |