Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668272 | 0.81 | EDNRB (0.38) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL1477982 | 0.81 | EDNRB (0.38) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL1695321 | 0.78 | HDAC9 (0.40) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL4630185 | 0.78 | HDAC9 (0.40) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL28476847 | 0.76 | KIF11 (0.37) | KIF11EDNRBEDNRAHDAC9 | |
| SCHEMBL28476843 | 0.76 | KIF11 (0.37) | KIF11EDNRBEDNRAHDAC9 | |
| SCHEMBL19644421 | 0.68 | MEN1 (0.40) | MEN1 | |
| SCHEMBL3732088 | 0.67 | HDAC9 (0.43) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL27956103 | 0.67 | HDAC9 (0.43) | KIF11EDNRBEDNRAHDAC9MEN1 | |
| SCHEMBL1404156 | 0.65 | HDAC9 (0.41) | KIF11EDNRBEDNRAHDAC9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922308-A2 | PROCESSES FOR OPTICAL RESOLUTION OF 1-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE | Teva Pharmaceutical Industries Ltd. (IL) | 2008-05-21 | — | — | EP | disclosed |
| WO-2008019055-A2 | PROCESSES FOR OPTICAL RESOLUTION OF 1-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-02-14 | — | — | WO | disclosed |