Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953043 | 0.86 | ADORA3 (0.36) | ADORA3GPR3MAPTGRIN2B | |
| SCHEMBL14994044 | 0.86 | CA1 (0.39) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL13807307 | 0.86 | NOTUM (0.45) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL1868624 | 0.81 | NOTUM (0.64) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL31401414 | 0.81 | NOTUM (0.64) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL1871974 | 0.80 | WDR5 (0.51) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL29482059 | 0.80 | WDR5 (0.51) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL16950549 | 0.80 | MRGPRX4 (0.38) | DDR1WDR5HDAC3HDAC1HDAC2 | |
| SCHEMBL1510479 | 0.80 | PGR (0.39) | CA1CA2CA7CA9NOTUM | |
| SCHEMBL12160006 | 0.80 | PGR (0.39) | CA1CA2CA7CA9NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |