Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700768 | 0.81 | NFE2L2 (0.39) | ERN1NFE2L2TDP1TSHRALDH1A1 | |
| SCHEMBL16961910 | 0.81 | NFE2L2 (0.39) | ERN1NFE2L2TDP1TSHRALDH1A1 | |
| SCHEMBL16962237 | 0.78 | NFE2L2 (0.54) | ERN1NFE2L2ALDH1A1 | |
| SCHEMBL16961854 | 0.78 | TSHR (0.48) | ERN1TDP1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL2897976 | 0.77 | ERN1 (0.41) | ERN1NFE2L2TDP1TSHRHSD17B10 | |
| SCHEMBL29958016 | 0.76 | ERN1 (0.59) | ERN1NFE2L2TDP1HSD17B10LMNA | |
| SCHEMBL42333 | 0.76 | ERN1 (0.59) | ERN1NFE2L2TDP1HSD17B10LMNA | |
| SCHEMBL16618763 | 0.76 | NFE2L2 (0.39) | ERN1NFE2L2TDP1TSHRALDH1A1 | |
| SCHEMBL20764886 | 0.76 | ERN1 (0.39) | ERN1NFE2L2TDP1TSHRHSD17B10 | |
| SCHEMBL5676565 | 0.76 | HPGD (0.53) | ERN1NFE2L2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |