Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.57 |
| ▸ | FPR1 | P21462 | 4/20 | 0.54 |
| ▸ | FPR2 | P25090 | 4/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695337 | 1.00 | FOLH1 (0.57) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066381 | 0.99 | FOLH1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066401 | 0.99 | FOLH1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066379 | 0.99 | FOLH1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066371 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066397 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066369 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066398 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066400 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R | |
| SCHEMBL27066357 | 0.96 | FPR1 (0.56) | FOLH1FPR1FPR2NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150118178-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | UNIV KANSAS (US) | 2015-04-30 | — | — | US | disclosed |
| US-8956604-B2 | Conjugates comprising an N-oxime bond and associated methods | THE UNIVERSITY OF KANSAS (US) | 2015-02-17 | — | — | US | disclosed |
| US-20130195791-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | THE UNIVERSITY OF KANSAS | 2013-08-01 | — | — | US | disclosed |
| EP-2585108-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | University Of Kansas (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011163568-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | UNIVERSITY OF KANSAS (US) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130195791-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | DOHH, HCCS, PRMT1 | FOLH1 586/4885FPR1 255/4885FPR2 397/4885 |
| US-20150118178-A1 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS | DOHH, HCCS, PRMT1 | FOLH1 586/4885FPR1 255/4885FPR2 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.