SCHEMBL27066400

SCHEMBL27066400

CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 4/20 0.56
FPR2 P25090 4/20 0.56
ACE P12821 6/20 0.55
FOLH1 Q04609 1/20 0.53
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
NPY4R P50391 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27066357 1.00 FPR1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066398 1.00 FPR1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066397 1.00 FPR1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066369 1.00 FPR1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066371 1.00 FPR1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066379 0.97 FOLH1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066401 0.97 FOLH1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL27066381 0.97 FOLH1 (0.56) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL1695336 0.96 FOLH1 (0.57) FPR1FPR2ACEFOLH1NPY1R
SCHEMBL1695337 0.96 FOLH1 (0.57) FPR1FPR2ACEFOLH1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024409-A1 N-f-MLF DERIVATIVES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE UNIVERSITY OF SOUTH ALABAMA (US) 2024-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024409-A1 N-f-MLF DERIVATIVES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE FPR1, FPR2, FPR3 FPR1 1/4885FPR2 2/4885ACE 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.