Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961608 | 0.80 | HTT (0.33) | ALDH1A1LMNAPDE4AKMT2ASMN1; SMN2 | |
| SCHEMBL16953498 | 0.79 | HPGD (0.34) | ALDH1A1LMNAPDE4AMEN1KMT2A | |
| SCHEMBL16958907 | 0.79 | KMT2A (0.40) | ALDH1A1LMNAPDE4AMEN1KMT2A | |
| SCHEMBL8189614 | 0.76 | PDE4A (0.42) | ALDH1A1LMNAPDE4AMEN1KMT2A | |
| SCHEMBL16960900 | 0.74 | TRPA1 (0.38) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16961269 | 0.73 | MEN1 (0.35) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL16952073 | 0.73 | MAPT (0.44) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL16961082 | 0.73 | TRPA1 (0.37) | ALDH1A1LMNAGAASMN1; SMN2TRPA1 | |
| SCHEMBL16950651 | 0.73 | TRPA1 (0.37) | ALDH1A1LMNASMN1; SMN2TRPA1MAPT | |
| SCHEMBL15693312 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |