Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953320 | 0.88 | GABRA1 (0.37) | MRGPRX4NPC1TP53RAB9ALMNA | |
| SCHEMBL16958923 | 0.86 | ELANE (0.35) | ELANENPC1TP53RAB9ALMNA | |
| SCHEMBL16954923 | 0.84 | ELANE (0.38) | ELANENPC1TP53RAB9ALMNA | |
| SCHEMBL16953918 | 0.81 | L3MBTL1 (0.38) | NPC1RAB9ALMNATSHRALDH1A1 | |
| SCHEMBL16958505 | 0.80 | ALDH1A1 (0.39) | NPC1RAB9ALMNATSHRALDH1A1 | |
| SCHEMBL16959311 | 0.80 | HCRTR1 (0.41) | LMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL16954987 | 0.79 | DAO (0.33) | LMNATSHRALDH1A1KDM4EDAO | |
| SCHEMBL16960828 | 0.79 | KAT6A (0.35) | MRGPRX4LMNAALDH1A1KDM4EDAO | |
| SCHEMBL22588822 | 0.78 | KMT2A (0.43) | MRGPRX4NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL16950579 | 0.78 | ALDH1A1 (0.41) | MRGPRX4NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |