Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952486 | 0.87 | MAPT (0.48) | TDP1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL16959952 | 0.86 | CYP19A1 (0.46) | TDP1SMN1; SMN2LMNAHTTTTR | |
| SCHEMBL16959328 | 0.86 | TDP1 (0.51) | TDP1SMN1; SMN2LMNAHTTTTR | |
| SCHEMBL16952073 | 0.83 | MAPT (0.44) | TDP1SMN1; SMN2LMNAHTTTTR | |
| SCHEMBL16961003 | 0.82 | AKR1C3 (0.41) | TDP1SMN1; SMN2LMNAHTTTTR | |
| SCHEMBL16956994 | 0.82 | SMN1; SMN2 (0.57) | TDP1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL16957705 | 0.81 | ALDH1A1 (0.51) | TDP1SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL16962137 | 0.79 | TDP1 (0.54) | TDP1SMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL16955468 | 0.79 | CYP1A2 (0.41) | TDP1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL16955947 | 0.79 | ALDH1A1 (0.42) | TDP1SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |