Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959245 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL16955947 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL16955468 | 0.83 | CYP1A2 (0.41) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL16961858 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRLMNAMAPTKMT2A | |
| SCHEMBL16954542 | 0.81 | PTPRC (0.39) | ALDH1A1TDP1TSHRCYP3A4LMNA | |
| SCHEMBL16959250 | 0.81 | HSD17B10 (0.51) | ALDH1A1TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16956326 | 0.81 | LMNA (0.40) | ALDH1A1TDP1TSHRLMNAALOX15 | |
| SCHEMBL16951947 | 0.81 | TXNRD1 (0.41) | ALDH1A1TDP1TSHRLMNAMAPT | |
| SCHEMBL16956291 | 0.81 | TDP1 (0.51) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL16957017 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |