Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953559 | 0.82 | LMNA (0.37) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL16960171 | 0.82 | TRPA1 (0.34) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL16957764 | 0.81 | TRPA1 (0.36) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL8191012 | 0.79 | GRIN2B (0.41) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL16957153 | 0.78 | NPC1 (0.33) | TRPA1LMNANPC1MAPTRAB9A | |
| SCHEMBL16961672 | 0.77 | CES2 (0.41) | ALDH1A1 | |
| SCHEMBL8205756 | 0.77 | CYP1A2 (0.42) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL16958798 | 0.76 | NQO1 (0.42) | LMNANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL25027436 | 0.76 | TRPA1 (0.38) | TRPA1LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL16952763 | 0.76 | PPARG (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |