Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953219 | 0.81 | KEAP1 (0.38) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL16961242 | 0.79 | SLC6A2 (0.37) | LMNASLC6A2SLC6A4CES2SLC6A3 | |
| SCHEMBL16954957 | 0.79 | HTT (0.39) | LMNASLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL7494317 | 0.78 | CES2 (0.44) | LMNADDR1CES2CES1MEN1 | |
| SCHEMBL16954445 | 0.77 | CES2 (0.52) | CES2CES1TRPA1MEN1KMT2A | |
| SCHEMBL16959391 | 0.76 | CES2 (0.36) | LMNACES2CES1TRPA1MEN1 | |
| SCHEMBL16953420 | 0.74 | F2R (0.40) | CES2CES1TRPA1MAPTKEAP1 | |
| SCHEMBL16959796 | 0.74 | CES2 (0.35) | CES2CES1TRPA1KEAP1 | |
| SCHEMBL11771246 | 0.74 | KEAP1 (0.53) | LMNADDR1CES2CES1MEN1 | |
| SCHEMBL16960076 | 0.74 | CES2 (0.35) | SLC6A2SLC6A4CES2CES1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |