Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954098 | 0.81 | CCR2 (0.40) | HTTHPGDADRA1DADRA1AADRA1B | |
| SCHEMBL16956499 | 0.79 | LMNA (0.37) | ADRA1DADRA1AADRA1BSLC6A4MEN1 | |
| SCHEMBL16961242 | 0.79 | SLC6A2 (0.37) | HPGDSLC6A4CCR2ALDH1A1KDM4E | |
| SCHEMBL7492153 | 0.78 | HTT (0.44) | HTTHPGDADRA1DADRA1AADRA1B | |
| SCHEMBL16954719 | 0.77 | ALDH1A1 (0.50) | HTTHPGDGABRA1GABRB1GABRG2 | |
| SCHEMBL16953758 | 0.76 | ALDH1A1 (0.37) | SLC6A4GABRA1GABRB1GABRG2GABRB3 | |
| SCHEMBL16960526 | 0.76 | CYP3A4 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL20053804 | 0.74 | ALDH1A1 (0.57) | HTTHPGDADRA1DADRA1AADRA1B | |
| SCHEMBL16952403 | 0.74 | ANO1 (0.36) | GABRA1GABRB1GABRG2GABRB3GABRB2 | |
| SCHEMBL16959406 | 0.74 | F2R (0.40) | HTTHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |