Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957888 | 0.85 | NOTUM (0.38) | HTR2CRARGRARB | |
| SCHEMBL16957296 | 0.82 | RARG (0.40) | RARGRARB | |
| SCHEMBL26049082 | 0.81 | ALDH1A1 (0.42) | HTR2CDRD2DRD4DRD3 | |
| SCHEMBL16955732 | 0.81 | TP53 (0.39) | HTR2CDRD2DRD4DRD3 | |
| SCHEMBL16962248 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL16952734 | 0.77 | — | — | |
| SCHEMBL16956425 | 0.77 | — | — | |
| SCHEMBL16951375 | 0.77 | KDM1A (0.32) | — | |
| SCHEMBL16951516 | 0.77 | PTGS1 (0.33) | — | |
| SCHEMBL16961639 | 0.77 | HTR2C (0.40) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |