Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343392 | 0.83 | ALDH1A3 (0.37) | ALDH1A1ALDH1A3CYP2A6 | |
| SCHEMBL16955732 | 0.81 | TP53 (0.39) | ALDH1A1TDP1HTR2CDRD2DRD4 | |
| SCHEMBL16956563 | 0.81 | HTR2C (0.35) | HTR2CDRD2DRD4DRD3 | |
| SCHEMBL8250780 | 0.77 | KDM4E (0.55) | ALDH1A1CYP2A6KDM4EPTGS2RAB9A | |
| SCHEMBL28056063 | 0.77 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3CYP2A6TSHRKDM4E | |
| SCHEMBL2979640 | 0.77 | ALDH1A1 (0.42) | ALDH1A1ALDH1A3CYP2A6TSHRKDM4E | |
| SCHEMBL24512766 | 0.77 | ALDH1A1 (0.55) | ALDH1A1ALDH1A3CYP2A6TSHRKDM4E | |
| SCHEMBL29955837 | 0.77 | ALDH1A1 (0.42) | ALDH1A1ALDH1A3CYP2A6TSHRKDM4E | |
| SCHEMBL8031193 | 0.77 | ALDH1A3 (0.49) | ALDH1A1ALDH1A3CYP2A6TDP1HSD17B10 | |
| SCHEMBL21459966 | 0.75 | HTR2C (0.36) | ALDH1A1ALDH1A3CYP2A6TSHRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Apollo Therapeutics Limited (GB) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CSNK1A1, CSNK1D, CSNK2A1 | ALDH1A1 2913/4885ALDH1A3 2318/4885CYP2A6 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.