SCHEMBL16962248

SCHEMBL16962248

O[CH]c1ccc(Cl)c(C2CC2)c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
OPRL1 P41146 7/20 0.35
GPR84 Q9NQS5 1/20 0.33
SIGMAR1 Q99720 2/20 0.31
TMEM97 Q5BJF2 1/20 0.31
EBP Q15125 1/20 0.31
IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16954310 0.85 SIGMAR1 (0.42) ALDH1A1MAPK1OPRL1SIGMAR1TMEM97
SCHEMBL16957296 0.82 RARG (0.40)
SCHEMBL24512766 0.81 ALDH1A1 (0.55) ALDH1A1MAPK1OPRL1SIGMAR1TMEM97
SCHEMBL16960202 0.81 ALDH1A1 (0.37) ALDH1A1MAPK1OPRL1GPR84SIGMAR1
SCHEMBL16956425 0.77
SCHEMBL16956563 0.77 HTR2C (0.35)
SCHEMBL16951375 0.77 KDM1A (0.32) OPRL1
SCHEMBL16952734 0.77
SCHEMBL16954306 0.74 MAOA (0.33)
SCHEMBL11874344 0.74 SIGMAR1 (0.37) ALDH1A1MAPK1OPRL1SIGMAR1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed