Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958687 | 0.84 | TRPV4 (0.49) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL30902420 | 0.84 | TRPV4 (0.52) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL16951588 | 0.81 | AR (0.47) | HPGDMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL30902406 | 0.80 | TRPV4 (0.46) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1402437 | 0.79 | TRPV4 (0.61) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL19511614 | 0.79 | MAOB (0.54) | CCR5GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16954818 | 0.79 | ALK (0.39) | TRPV4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16959915 | 0.78 | TRPV4 (0.47) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL16952167 | 0.78 | TRPV4 (0.53) | TRPV4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL16959161 | 0.76 | CYP2A6 (0.44) | TRPV4MEN1KMT2AALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |