Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956583 | 0.80 | TRPV4 (0.52) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30902420 | 0.80 | TRPV4 (0.52) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16958687 | 0.80 | TRPV4 (0.49) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31581221 | 0.77 | TRPV4 (0.44) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27341301 | 0.77 | TSHR (0.59) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1402437 | 0.76 | TRPV4 (0.61) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16952167 | 0.74 | TRPV4 (0.53) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15869350 | 0.74 | TRPV4 (0.56) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1964286 | 0.74 | TRPV4 (0.56) | TRPV4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6944897 | 0.74 | TRPV4 (0.56) | TRPV4PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619097-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107434-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |