Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952283 | 0.86 | CYP4F2 (0.47) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16959092 | 0.81 | CYP4F2 (0.63) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL16956859 | 0.81 | LMNA (0.47) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL16961649 | 0.80 | PTPN1 (0.46) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL10183039 | 0.80 | CYP4F2 (0.58) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16955131 | 0.80 | PTPN1 (0.43) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL16955132 | 0.80 | THRB (0.45) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL16955520 | 0.79 | CYP4F2 (0.42) | PTPN1PTPN11CYP4F2CYP4A11THRB | |
| SCHEMBL16957669 | 0.79 | CYP4F2 (0.44) | CYP4F2CYP4A11ALOX5LMNAKDM4E | |
| SCHEMBL16961651 | 0.78 | PTPN1 (0.42) | PTPN1PTPN11CYP4F2CYP4A11THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |