Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961108 | 0.91 | ALOX5 (0.43) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16955768 | 0.88 | CYP4F2 (0.44) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16958037 | 0.82 | LMNA (0.46) | CYP4F2CYP4A11MAPTLMNAALDH1A1 | |
| SCHEMBL16950784 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11ALOX5MAPTLMNA | |
| SCHEMBL16956856 | 0.80 | PTPN1 (0.46) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16954158 | 0.79 | PTGS2 (0.44) | PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL16950805 | 0.78 | KMT2A (0.40) | CYP4F2CYP4A11MAPTLMNAALDH1A1 | |
| SCHEMBL16958096 | 0.78 | NQO1 (0.39) | THRBMAPTHTTRAB9AMEN1 | |
| SCHEMBL16959092 | 0.78 | CYP4F2 (0.63) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 | |
| SCHEMBL16956859 | 0.78 | LMNA (0.47) | PTPN1PTPN11CYP4F2CYP4A11ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |