Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958945 | 0.85 | KDM4E (0.40) | NOTUMKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL16952864 | 0.85 | NPC1 (0.33) | NOTUMALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL16950991 | 0.83 | ALDH1A1 (0.37) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL16955270 | 0.81 | CYP1A2 (0.41) | NOTUMKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL16953308 | 0.81 | NOTUM (0.36) | NOTUMKDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL16951507 | 0.81 | NOTUM (0.32) | NOTUMALDH1A1 | |
| SCHEMBL16960857 | 0.80 | KDM4E (0.44) | NOTUMKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL16952623 | 0.80 | DYRK1A (0.33) | DYRK1A | |
| SCHEMBL16957978 | 0.80 | MAPK10 (0.30) | KDM4E | |
| SCHEMBL16961491 | 0.79 | GABRA1 (0.37) | ALDH1A1KMT2AMRGPRX4HTTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |