Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957405 | 0.85 | NOTUM (0.41) | GAAKMT2AMEN1NOTUMTAS1R3 | |
| SCHEMBL16953157 | 0.84 | TSHR (0.32) | TSHRSMN1; SMN2CES2CES1TAS1R3 | |
| SCHEMBL16962154 | 0.84 | KMT2A (0.34) | NPC1GAAKMT2ACES2CES1 | |
| SCHEMBL16955633 | 0.83 | NPC1 (0.33) | NPC1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL16957067 | 0.81 | NPC1 (0.32) | NPC1 | |
| SCHEMBL16953321 | 0.81 | NPC1 (0.32) | NPC1 | |
| SCHEMBL16953721 | 0.80 | GABRA1 (0.37) | NPC1TSHRALDH1A1 | |
| SCHEMBL16961310 | 0.80 | TSHR (0.36) | TSHRKMT2AMEN1NOTUMSMN1; SMN2 | |
| SCHEMBL16958222 | 0.79 | NOTUM (0.34) | NPC1GAATSHRNOTUMALDH1A1 | |
| SCHEMBL16956745 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1NOTUMTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |