Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950409 | 0.85 | TRPV4 (0.37) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL16959300 | 0.83 | MAOB (0.38) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL16959596 | 0.83 | IMPDH2 (0.33) | TRPV4CYP11B2CYP11B1 | |
| SCHEMBL16955533 | 0.81 | AR (0.37) | MAOAMAOBCYP11B2CYP11B1FFAR1 | |
| SCHEMBL16962201 | 0.81 | CYP2A6 (0.39) | TRPV4MAOAMAOBAR | |
| SCHEMBL16952493 | 0.79 | CYP11B1 (0.41) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL16958723 | 0.79 | TRPV4 (0.40) | TRPV4MAOAMAOBCYP11B2CYP11B1 | |
| SCHEMBL16959905 | 0.76 | CYP11B1 (0.44) | MAOAMAOBCYP11B2CYP11B1AR | |
| SCHEMBL16951137 | 0.76 | TRPV4 (0.46) | TRPV4CYP11B2CYP11B1 | |
| SCHEMBL16961672 | 0.76 | CES2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |