Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196373 | 0.84 | NFE2L2 (0.48) | NFE2L2RELATRPA1MAOB | |
| SCHEMBL16960382 | 0.83 | ALDH1A1 (0.32) | NFE2L2 | |
| SCHEMBL3715365 | 0.79 | NFE2L2 (0.41) | NFE2L2PTGS2ERN1TRPA1CES2 | |
| SCHEMBL8380098 | 0.74 | NFE2L2 (0.37) | NFE2L2PTGS2ERN1TRPA1CES2 | |
| SCHEMBL16960012 | 0.74 | NFE2L2 (0.41) | NFE2L2RELAPTGS2ERN1CES2 | |
| SCHEMBL16958387 | 0.71 | NFE2L2 (0.37) | NFE2L2PTGS2ERN1CES2BCHE | |
| SCHEMBL16960534 | 0.71 | HTR1B (0.37) | ERN1TRPA1L3MBTL1 | |
| SCHEMBL16960264 | 0.71 | NFE2L2 (0.37) | NFE2L2PTGS2ERN1CES2BCHE | |
| SCHEMBL28054812 | 0.70 | TAAR1 (0.42) | NFE2L2PTGS2 | |
| SCHEMBL16951025 | 0.70 | PTGS2 (0.36) | NFE2L2PTGS2ERN1TRPA1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |