Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953600 | 0.84 | KMT2A (0.50) | MAPK1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL16953412 | 0.83 | LTA4H (0.53) | CYP1A2CYP2C19KMT2A | |
| SCHEMBL2971332 | 0.83 | EGFR (0.46) | MAPK1CYP1A2CYP2D6CYP2C19SYK | |
| SCHEMBL30924197 | 0.83 | EGFR (0.46) | MAPK1CYP1A2CYP2D6CYP2C19SYK | |
| SCHEMBL2908379 | 0.83 | TBXAS1 (0.52) | MAPK1CYP1A2CYP2D6CYP2C19TBXAS1 | |
| SCHEMBL29996269 | 0.83 | TBXAS1 (0.52) | MAPK1CYP1A2CYP2D6CYP2C19TBXAS1 | |
| SCHEMBL15723552 | 0.81 | MAPK1 (0.58) | MAPK1CYP1A2CYP2D6CYP2C19SYK | |
| SCHEMBL16961798 | 0.81 | ALDH1A1 (0.57) | CYP2D6SYKALDH1A1KMT2ATBXAS1 | |
| SCHEMBL16956896 | 0.81 | TBXAS1 (0.38) | MAPK1ALDH1A1LMNATBXAS1 | |
| SCHEMBL694324 | 0.80 | TP53 (0.53) | MAPK1CYP1A2CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |