Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961356 | 0.81 | KMT2A (0.36) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL29276547 | 0.80 | TSHR (0.57) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL16959460 | 0.80 | KMT2A (0.36) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL3787197 | 0.79 | MAPT (0.44) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL16952148 | 0.75 | ALDH1A1 (0.37) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL16957333 | 0.75 | ALDH1A1 (0.37) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL2162442 | 0.74 | TSHR (0.50) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL10706917 | 0.73 | TSHR (0.58) | ALDH1A1HTTLMNATSHR | |
| SCHEMBL1146294 | 0.73 | MAPT (0.53) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL12093642 | 0.71 | MAPT (0.40) | KMT2AMAPTMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |