Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952094 | 0.81 | LMNA (0.37) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL28048727 | 0.80 | POLB (0.48) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL16953025 | 0.80 | ALDH1A1 (0.33) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL28858278 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL23714659 | 0.76 | GAA (0.53) | ALDH1A1LMNAKMT2AGAAMAPT | |
| SCHEMBL16957333 | 0.75 | ALDH1A1 (0.37) | ALDH1A1HTTKMT2AGAAMEN1 | |
| SCHEMBL16958247 | 0.75 | KMT2A (0.40) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL11758277 | 0.74 | AKR1C3 (0.47) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL470074 | 0.74 | ADRB1 (0.38) | ALDH1A1LMNAHTTKMT2AGAA | |
| SCHEMBL29722828 | 0.73 | CES2 (0.38) | LMNAKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |