Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958247 | 0.81 | KMT2A (0.40) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL16961211 | 0.79 | KMT2A (0.34) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL16952094 | 0.79 | LMNA (0.37) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL16956070 | 0.77 | MAPT (0.37) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL16956072 | 0.77 | TSHR (0.50) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL16953376 | 0.76 | TSHR (0.45) | KMT2AMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL16951879 | 0.76 | P2RX7 (0.38) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL16961299 | 0.75 | ALDH1A1 (0.35) | KMT2AMAPTMEN1GAAALDH1A1 | |
| SCHEMBL16955650 | 0.74 | CYP11B1 (0.40) | KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL16951855 | 0.74 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |