Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954409 | 0.87 | ALOX5 (0.36) | MRGPRX4ALDH1A1LMNA | |
| SCHEMBL16952126 | 0.85 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1LMNAMAPT | |
| SCHEMBL16961344 | 0.85 | GABRA1 (0.38) | GABRA1GABRB2MRGPRX4ALDH1A1LMNA | |
| SCHEMBL16952080 | 0.84 | GABRA1 (0.39) | GABRA1GABRB2MRGPRX4CLCN2ADRA2A | |
| SCHEMBL16956118 | 0.84 | GABRA1 (0.43) | GABRA1GABRB2MRGPRX4ALDH1A1LMNA | |
| SCHEMBL16960493 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTTP53NPC1 | |
| SCHEMBL1648373 | 0.79 | MRGPRX4 (0.55) | GABRA1GABRB2MRGPRX4ALDH1A1LMNA | |
| SCHEMBL16962927 | 0.79 | KMT2A (0.50) | ALDH1A1MAPTTP53NPC1MAPK1 | |
| SCHEMBL16952465 | 0.79 | CA1 (0.44) | ALDH1A1LMNAMAPTTP53NPC1 | |
| SCHEMBL16950705 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2MRGPRX4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |